Simultaneous Estimation of Atorvastatin and Aspirin in Bulk and Capsule Dosage Form by Chemometric Assisted Spectrophotometric Methods
نویسندگان
چکیده
منابع مشابه
Spectrophotometric methods for simultaneous estimation of rabeprazole sodium and aceclofenac from the combined capsule dosage form
INTRODUCTION The present work aimed to develop and validate spectrophotometric methods for simultaneous estimation of rabeprazole sodium and aceclofenac in a pure and capsule dosage form. MATERIALS AND METHODS Method 1 is based on solving a simultaneous equation. Absorbances of rabeprazole sodium and aceclofenac were measured at their respective absorbance maximas (λ max) of 283 and 276 nm. M...
متن کاملChemometric Simultaneous Estimation of Clopidogrel Bisulphate and Aspirin from Combined Dosage Form
Two chemometric methods, inverse least square and classical least square, were applied to simultaneous assay of clopidogrel bisulphate and aspirin in their combined dosage tablet formulation. Twelve mixed solutions were prepared for the chemometric calibration as training set and 10 mixed solutions were prepared as validation set. The absorbance data matrix was obtained by measuring the absorba...
متن کاملValidated Spectrophotometric Method for Simultaneous Estimation of Atorvastatin and Nicotinic acid in Combined Pharmaceutical dosage form
A simple, precise and cost effective spectrophotometric method have been developed for the estimation Atorvastatin and Nicotinic acid in combination in tablet dosage form by UV spectroscopy, using multi-component mode of analysis. Methanol used as solvent λmax of Atorvastatin and Nicotinic acid was found to be 248nm and 261.5nm respectively. The method shows linearity in the Atorvastatin and Ni...
متن کاملSimultaneous Spectrophotometric Estimation of Esomeprazole and Naproxen in Bulk and Tablet Dosage Form
Esomeprzole and naproxen are available in tablet dosage form in the ratio 1:25. Two simple, accurate, precise and economic methods; simultaneous equation method and multicomponent method have been described for the simultaneous estimation of esomeprzole and naproxen in tablet dosage form. Absorption maxima of esomeprzole and naproxen in distilled water were found to be 301.0 nm and 262.0 nm res...
متن کاملSimultaneous UV spectrophotometric determination of Atorvastatin calcium and Telmisartan in tablet dosage form
Two accurate, precise, sensitve and economical procedures for simultaneous estimation of atorvastatin calcium and telmisartan in tablet dosage forms have been developed. First method employs formation and solving of simultaneous equations using 219 nm and 257nm as two analytical wavelengths for both drugs in 0.1 N NaOH. The second method is Qanalysis based on measurement of absorptivity at 240n...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Young Pharmacists
سال: 2016
ISSN: 0975-1483,0975-1505
DOI: 10.5530/jyp.2016.4.19